國外醫學期刊刊載研究 證實有用
‧ Human prostatic steroid 5 alpha-reductase isoforms--a comparative study of selective inhibitors.
This study suggests that Fenistride (active ingredient of Propecia) only inhibited the Type 2 form of 5 alpha reductase where Saw Palmetto extract inhibited both type 1 and 2 forms of 5 alpha-reductase and was more potent than Fenistride. J Steroid Biochem Mol Biol, 54: 5-6, 1995 Sep, 273-9
‧ Testosterone metabolism in primary cultures of human prostate epithelial cells and fibroblasts.
This Study shows that Fenistride and 4-MA inhibited the formation of some testostrone Metabolites (including DHT), where as Saw Palmetto inhibited the formation of all the Testostrone metabolites studied. J Steroid Biochem Mol Biol, 55: 3-4, 1995 Dec, 375-83
‧ The effect of Permixon on androgen receptors.
This study shows that Saw Palmetto extract was able to effectively reduce Binding of Testostrone and DHT to their receptors on various tissues. Acta Obstet Gynecol Scand, 67: 5, 1988, 397-9
‧ Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med. 2002 Apr;8(2):143-52
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